SCHEMBL9625901

SCHEMBL9625901

Fc1ncnc(F)c1C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.36
CHKA P35790 1/20 0.36
NOTUM Q6P988 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11991596 0.83 CA2 (0.30) CA2CHKA
SCHEMBL152324 0.78 PDPK1 (0.35)
SCHEMBL11001227 0.78 ALDH1A1 (0.36)
SCHEMBL25673629 0.73
SCHEMBL11231512 0.69 NOS3 (0.34) NOTUM
SCHEMBL26313685 0.69 CA2 (0.34) CA2CHKANOTUM
SCHEMBL12264312 0.69 CA2 (0.44) CA2CHKA
SCHEMBL83611 0.67
SCHEMBL9435934 0.67
SCHEMBL1437045 0.67 MEN1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0321784-B1 FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS BAYER AG (DE) 1992-03-18 EP disclosed
EP-0235729-B1 REACTIVE DYES BAYER AG (DE) 1990-12-19 EP disclosed
EP-0203505-B1 DISAZO METAL COMPLEX DYES BAYER AG (DE) 1989-05-24 EP disclosed
EP-0186812-B1 REACTIVE DYES BAYER AG (DE) 1989-01-25 EP disclosed
EP-0192067-B1 DISAZO DYES BAYER AG (DE) 1988-06-01 EP disclosed
EP-0235729-A2 Reactive dyes BAYER AG (DE) 1987-09-09 EP disclosed
EP-0128340-B1 REACTIVE DISAZO DYES BAYER AG (DE) 1987-05-27 EP disclosed
EP-0203505-A1 Disazo metal complex dyes BAYER AG (DE) 1986-12-03 EP disclosed
US-4621138-A Triphendioxazine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1986-11-04 US disclosed
EP-0192067-A1 Disazo dyes BAYER AG (DE) 1986-08-27 EP disclosed
EP-0186812-A2 Reactive dyes BAYER AG (DE) 1986-07-09 EP disclosed
EP-0158882-A2 Triphenedioxazine dyes BAYER AG (DE) 1985-10-23 EP disclosed
EP-0128316-A1 Reactive disazo dyes BAYER AG (DE) 1984-12-19 EP disclosed
EP-0128340-A1 Reactive disazo dyes BAYER AG (DE) 1984-12-19 EP disclosed
US-4007164-A FIBER-REACTIVE, CELLULOSE, WOOL BAYER AKTIENGESELLSCHAFT (DT) 1977-02-08 US disclosed