Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23545659 | 0.93 | HRH3 (0.50) | HRH3POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10953965 | 0.78 | HRH3 (0.88) | HRH3POLBALDH1A1TSHRHDAC1 | |
| SCHEMBL5561161 | 0.78 | ALDH1A1 (0.70) | HRH3POLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8808286 | 0.77 | HRH3 (0.57) | HRH3POLBALDH1A1TSHRHDAC1 | |
| SCHEMBL5074162 | 0.77 | HDAC6 (0.52) | POLBALDH1A1TSHRHDAC1SMN1; SMN2 | |
| SCHEMBL5561106 | 0.77 | ALDH1A1 (0.68) | HRH3POLBALDH1A1TSHRHDAC1 | |
| SCHEMBL8810030 | 0.76 | HRH3 (0.60) | HRH3POLBALDH1A1TSHRHDAC1 | |
| SCHEMBL2645047 | 0.75 | HRH3 (0.69) | HRH3POLBALDH1A1HDAC1CXCL12 | |
| SCHEMBL8494718 | 0.75 | HRH3 (0.59) | HRH3POLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL30471885 | 0.75 | PABPC1 (0.42) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116838-A | GUANIDINE DERIVATIVES AND FUNGICIDES FOR AGRICULTURE AND HORTICULTURE CONTAINING THE SAME | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0429281-A2 | Guanidine derivatives and fungicides for agriculture and horticulture containing the same | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1991-05-29 | — | — | EP | disclosed |