Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625452 | 0.74 | SMN1; SMN2 (0.44) | AGERMTNR1AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2814615 | 0.74 | AGER (0.67) | AGERMTNR1AL3MBTL1G6PC1OPRM1 | |
| SCHEMBL9057640 | 0.72 | CYP2C19 (0.53) | G6PC1MAPK1CCR5KCNH2SLC18A3 | |
| SCHEMBL11441244 | 0.70 | MAPT (0.51) | UBE2MDCUN1D1CYP2C19MEN1ALDH1A1 | |
| SCHEMBL9456418 | 0.70 | AGER (0.58) | AGERMTNR1AL3MBTL1OPRM1MAPK1 | |
| SCHEMBL14373102 | 0.69 | ATM (0.50) | CYP2C19MEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL23175993 | 0.68 | AGER (0.63) | AGERMTNR1AL3MBTL1OPRM1MAPK1 | |
| SCHEMBL22448034 | 0.68 | AGER (0.49) | AGERMTNR1AL3MBTL1G6PC1OPRM1 | |
| SCHEMBL29057240 | 0.68 | AGER (0.46) | AGERMTNR1AL3MBTL1G6PC1OPRM1 | |
| SCHEMBL7603670 | 0.67 | HRH3 (0.73) | AGERG6PC1MAPK1SLC18A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116838-A | GUANIDINE DERIVATIVES AND FUNGICIDES FOR AGRICULTURE AND HORTICULTURE CONTAINING THE SAME | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0429281-A2 | Guanidine derivatives and fungicides for agriculture and horticulture containing the same | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1991-05-29 | — | — | EP | disclosed |