Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28448952 | 0.82 | DAO (0.51) | DAOMRGPRX4CDC7DBF4HRH3 | |
| SCHEMBL15023264 | 0.80 | KIF11 (0.49) | DAOCDC7DBF4HRH3GSK3A | |
| SCHEMBL30429240 | 0.77 | MRGPRX4 (0.48) | MRGPRX4SCN8AHRH3FOLH1GLA | |
| SCHEMBL9626110 | 0.76 | TP53 (0.48) | DAOCDC7DBF4TP53ALDH1A1 | |
| SCHEMBL7391468 | 0.75 | CYP2C19 (0.50) | MEN1ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL7388300 | 0.73 | CYP2C19 (0.48) | MEN1ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL6011460 | 0.73 | GLS (0.50) | DAOMRGPRX4SCN8AHRH3GLA | |
| SCHEMBL9626741 | 0.73 | HTR2A (0.46) | DAOCDC7DBF4EPHX1MAPT | |
| SCHEMBL18405 | 0.73 | GLA (0.50) | DAOMRGPRX4HRH3GSK3BFOLH1 | |
| SCHEMBL29386535 | 0.73 | GLA (0.50) | DAOMRGPRX4HRH3GSK3BFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326297-B1 | THIOFORMAMIDE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1992-03-18 | — | — | EP | disclosed |
| US-4959385-A | MUSCLE RELAXANTS | MAY & BAKER LIMITED (GB) | 1990-09-25 | — | — | US | disclosed |
| EP-0326297-A1 | Thioformamide derivatives | MAY & BAKER LIMITED (GB) | 1989-08-02 | — | — | EP | disclosed |