SCHEMBL18405

SCHEMBL18405

N#Cc1cccc(CCl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.50
MRGPRX4 Q96LA9 2/20 0.49
CYP19A1 P11511 1/20 0.47
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
HRH3 Q9Y5N1 1/20 0.47
MEP1A Q16819 1/20 0.45
MEP1B Q16820 1/20 0.45
ENPP2 Q13822 1/20 0.44
ALDH1A1 P00352 1/20 0.43
KDM1A O60341 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
CNR1 P21554 1/20 0.42
DAO P14920 1/20 0.42
IDH1 O75874 1/20 0.42
FFAR1 O14842 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386535 1.00 GLA (0.50) GLAMRGPRX4CYP19A1CYP11B1CYP11B2
SCHEMBL9714736 0.86 MAOA (0.42) GLAMRGPRX4CYP19A1CYP11B1CYP11B2
SCHEMBL2154019 0.82 GLA (0.53) GLAMRGPRX4CYP19A1CYP11B1CYP11B2
SCHEMBL2153847 0.82 HRH3 (0.59) GLAMRGPRX4CYP19A1CYP11B1CYP11B2
SCHEMBL30429240 0.80 MRGPRX4 (0.48) GLAMRGPRX4CYP19A1CYP11B1CYP11B2
SCHEMBL5090668 0.80 GLA (0.51) GLAMRGPRX4CYP19A1CYP11B1CYP11B2
SCHEMBL1477359 0.80 HRH3 (0.43) CYP19A1CYP11B1CYP11B2HRH3FFAR1
SCHEMBL5158276 0.78 TSHR (0.46) GLAMRGPRX4CYP19A1CYP11B1CYP11B2
SCHEMBL8733205 0.78 TSHR (0.41) GLAMRGPRX4CYP19A1CYP11B1CYP11B2
SCHEMBL3063453 0.78 ENPP2 (0.53) GLAMRGPRX4CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115959962-B Visible light-promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
CN-114133352-B Viologen coordination compound crystal and preparation method thereof 南京米兰达视光科学研究院有限公司 2025-03-11 CN claimed
CN-118258909-A Method for measuring content of p-cyanobenzyl chloride and isomers thereof in letrozole 河北以岭医药研究院有限公司 2024-06-28 CN claimed
US-20240067770-A1 POLYTHIOL COMPOSITION AND OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME SK PUCORE CO., LTD. (KR) 2024-02-29 US claimed
EP-4209526-A1 POLYTHIOL COMPOSITION AND OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME SKC Co., Ltd. (KR) 2023-07-12 EP claimed
CN-115989280-A Polythiol composition and optical polymerizable composition comprising the same SKC株式会社 2023-04-18 CN claimed
CN-114133352-A Viologen coordination compound crystal and preparation method thereof 南京米兰达视光科学研究院有限公司 2022-03-04 CN claimed
CN-112705267-A High-efficiency photocatalyst and preparation method thereof 泗县唯澳生物技术开发有限公司 2021-04-27 CN claimed
CN-108538606-B Solid electrolyte of dye-sensitized solar cell and preparation method thereof 西安智财全技术转移中心有限公司 2020-06-16 CN claimed
US-10590145-B2 Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent SHANDONG UNIVERSITY (CN) 2020-03-17 US claimed
CN-108538606-A A kind of dye-sensitized solar cells solid electrolyte and preparation method thereof 山东冬瑞高新技术开发有限公司 2018-09-14 CN claimed
US-20180201576-A1 METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER SOOCHOW UNIVERSITY (CN) 2018-07-19 US claimed
EP-3129352-B1 METHOD FOR MANUFACTURING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE COVESTRO DEUTSCHLAND AG (DE) 2017-11-15 EP claimed
US-20170121449-A1 COMPOSITION FOR PRODUCING TRANSPARENT POLYTHIOURETHANE BODIES MITSUI CHEMICALS, INC. (JP) 2017-05-04 US claimed
CN-106459357-A Aromatic nitrile-containing compositions for making transparent polythiourethane articles 科思创德国股份有限公司 2017-02-22 CN claimed
US-20170029552-A1 COMPOSITION CONTAINING AROMATIC NITRILES FOR THE PRODUCTION OF TRANSPARENT POLYTHIOURETHANE BODIES COVESTRO DEUTSCHLAND AG (DE) 2017-02-02 US claimed
CN-103214396-A Production method of 3-cyanobenzoic acid UNIV HUBEI TECHNOLOGY 2013-07-24 CN claimed
EP-1004574-B1 Process for producing cyanobenzyl compounds SHOWA DENKO KK (JP) 2003-03-19 EP claimed
US-6187945-B1 TRANSFORMING AN AMINOMETHYL GROUP OF A CYANOBENZYLAMINE COMPOUND INTO A HYDROXYMETHYL GROUP, A HALOMETHYL GROUP, OR AN ACYLOXYMETHYL GROUP BY DIAZOTIZATION AND HYDROXYLATION, HALOGENATION OR ACYLATION SHOWA DENKO K.K. (JP) 2001-02-13 US claimed
EP-1004574-A1 Process for producing cyanobenzyl compounds Showa Denko Kabushiki Kaisha (JP) 2000-05-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10590145-B2 Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent TYMP, DPYD, TPMT GLA 1043/4885MRGPRX4 2327/4885CYP19A1 2952/4885
US-20180201576-A1 METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER STS, TST, SCLY GLA 458/4885MRGPRX4 2715/4885CYP19A1 1194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.