Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 2/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15301042 | 0.85 | MEN1 (0.83) | PDE5AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8171663 | 0.85 | MEN1 (0.83) | PDE5AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9514571 | 0.85 | MEN1 (0.78) | PDE5AMAOAMAOBMEN1KMT2A | |
| SCHEMBL12496095 | 0.83 | PDE5A (1.00) | PDE5AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10362296 | 0.83 | EGFR (0.81) | PDE5AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15301347 | 0.83 | MEN1 (0.82) | PDE5AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15301136 | 0.83 | KDM4E (0.88) | PDE5AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23052404 | 0.82 | MEN1 (0.73) | MAOAMAOBMEN1KMT2AKDM4E | |
| SCHEMBL395608 | 0.82 | MEN1 (0.73) | MAOAMAOBMEN1KMT2AKDM4E | |
| SCHEMBL21531879 | 0.80 | L3MBTL1 (0.64) | MAOAMAOBMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201725-B1 | ELECTROPHOTOGRAPHIC REGISTRATION MATERIAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-18 | — | — | EP | claimed |
| US-4681827-A | OXAZOLE, OXADIAZOLE, HYDRAZONE OR PYRAZOLINE; PHOTOCONDUCTIVITY; RECORDING | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | claimed |
| EP-0201725-A2 | Electrophotographic registration material | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-11-20 | — | — | EP | claimed |
| EP-0201725-B1 | ELECTROPHOTOGRAPHIC REGISTRATION MATERIAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4681827-A | OXAZOLE, OXADIAZOLE, HYDRAZONE OR PYRAZOLINE; PHOTOCONDUCTIVITY; RECORDING | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | disclosed |
| EP-0201725-A2 | Electrophotographic registration material | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-11-20 | — | — | EP | disclosed |