Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626522 | 0.73 | MAOB (0.60) | — | |
| SCHEMBL9626517 | 0.73 | FFAR1 (0.42) | IDO1TDO2FFAR1TACR1 | |
| SCHEMBL5411666 | 0.72 | CASR (0.49) | IDO1FFAR1TACR1CACNA2D1SLC6A2 | |
| SCHEMBL9626408 | 0.72 | MAOB (0.57) | — | |
| SCHEMBL10314841 | 0.71 | CYP3A4 (0.58) | IDO1TACR1CYP3A4AGXT | |
| SCHEMBL9627112 | 0.71 | MAOB (0.58) | — | |
| SCHEMBL9628042 | 0.70 | MAOB (0.61) | — | |
| SCHEMBL178510 | 0.70 | PNMT (0.65) | SLC6A4SLC6A2 | |
| SCHEMBL10859369 | 0.69 | CHRNB2 (0.70) | IDO1TDO2TACR1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL23524229 | 0.69 | PNMT (0.62) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |