Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628202 | 0.76 | MAOB (0.54) | FFAR1MAOBPKMALOX5 | |
| SCHEMBL9628072 | 0.75 | MAOB (0.66) | MAOBPKMALOX5 | |
| SCHEMBL20622322 | 0.74 | SLC6A9 (0.37) | — | |
| SCHEMBL21747667 | 0.74 | RIPK1 (0.40) | FFAR1MAOBRIPK1 | |
| SCHEMBL19564591 | 0.74 | RIPK1 (0.40) | FFAR1MAOBRIPK1 | |
| SCHEMBL30439007 | 0.74 | OPRK1 (0.38) | TACR1 | |
| SCHEMBL31407768 | 0.73 | CTSL (0.43) | FFAR1IDO1TDO2MAOBCTSL | |
| SCHEMBL9626415 | 0.73 | SLC6A4 (0.49) | FFAR1IDO1TDO2TACR1 | |
| SCHEMBL29540073 | 0.72 | CTSL (0.49) | MAOBCTSLPKMALOX5RIPK1 | |
| SCHEMBL15083607 | 0.72 | CTSL (0.49) | MAOBCTSLPKMALOX5RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |