⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628034 | 0.70 | — | — | |
| SCHEMBL20554342 | 0.70 | — | — | |
| SCHEMBL20553991 | 0.65 | ACHE (0.31) | — | |
| SCHEMBL27943300 | 0.64 | CYP1A2 (0.33) | — | |
| SCHEMBL853354 | 0.58 | — | — | |
| Fluoride SCHEMBL28315957 | 0.56 | — | — | |
| Hydrochloric Acid SCHEMBL852482 | 0.56 | — | — | |
| Nitrogen SCHEMBL28012731 | 0.55 | LMNA (0.44) | — | |
| SCHEMBL898960 | 0.55 | — | — | |
| SCHEMBL105038 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339286-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-27 | — | — | EP | disclosed |
| EP-2427426-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| US-9738595-B2 | Carboxamide compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-22 | — | — | US | disclosed |
| EP-2961737-B1 | NOVEL CARBOXAMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-26 | — | — | EP | disclosed |
| US-20160002149-A1 | NOVEL CARBOXAMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-07 | — | — | US | disclosed |
| WO-2013092942-A1 | USE OF AMINOBENZAMIDE DERIVATIVES FOR CONTROLLING ANIMAL PARASITES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-22 | — | — | US | disclosed |
| US-5118694-A | Hypotensive agents; treatment for cardiovascular and muscular disorders | HOFFMANN-LA ROCHE INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-4971982-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, SMOOTH MUSCLE DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1990-11-20 | — | — | US | disclosed |
| US-4009168-A | STABILIZERS FOR POLYOLEFINS | UBE INDUSTRIES, LTD. (JA) | 1977-02-22 | — | — | US | disclosed |