SCHEMBL9626458

SCHEMBL9626458

C#CC#Cc1ccc2ccccc2c1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.43
CYP1A1 P04798 2/20 0.43
CYP1B1 Q16678 2/20 0.43
ASIC3 Q9UHC3 2/20 0.41
ACACB O00763 1/20 0.37
CYP2A6 P11509 5/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP3A4 P08684 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
HRH3 Q9Y5N1 1/20 0.35
PYCR1 P32322 1/20 0.35
MELK Q14680 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7702432 0.87 CYP1A2 (0.48) CYP1A2CYP1A1CYP1B1ASIC3ACACB
SCHEMBL5573799 0.82 ASIC3 (0.53) CYP1A2CYP1A1CYP1B1ASIC3ACACB
SCHEMBL29750775 0.78 CYP1A1 (0.58) CYP1A2CYP1A1CYP1B1CYP2A6ALDH1A1
SCHEMBL30375647 0.78 CYP1A1 (0.58) CYP1A2CYP1A1CYP1B1CYP2A6ALDH1A1
SCHEMBL825806 0.78 CYP1A1 (0.58) CYP1A2CYP1A1CYP1B1CYP2A6ALDH1A1
SCHEMBL30447338 0.76 ASIC3 (0.63) CYP1A2CYP1A1CYP1B1ASIC3ACACB
SCHEMBL10705668 0.76 ASIC3 (0.63) CYP1A2CYP1A1CYP1B1ASIC3ACACB
SCHEMBL5573818 0.75 ASIC3 (0.52) CYP1A2CYP1A1CYP1B1ASIC3ACACB
SCHEMBL5572006 0.75 ASIC3 (0.52) CYP1A2CYP1A1CYP1B1ASIC3ACACB
SCHEMBL23883181 0.74 CYP1A2 (0.50) CYP1A2CYP1A1CYP1B1ASIC3ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091488-A POLYETHYLACETYLENE DERIVATIVE AND PROCESS FOR PREPARATION THEREOF DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1992-02-25 US disclosed