Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030271 | 0.89 | POLB (0.60) | POLBKDM4ELMNAMAPK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9618940 | 0.88 | POLB (0.59) | POLBKDM4ELMNAMAPK1CYP1A2 | |
| SCHEMBL7754052 | 0.83 | ABCB1 (0.69) | KDM4ELMNACYP1A2AGTR1ABCB1 | |
| Oxybenzone SCHEMBL9626888 | 0.82 | HPGD (0.79) | POLBKDM4ELMNAMAPK1CYP1A2 | |
| SCHEMBL29260273 | 0.82 | POLB (0.67) | POLBKDM4ELMNAMAPK1CYP1A2 | |
| SCHEMBL30205105 | 0.81 | NPC1 (0.81) | POLBKDM4ELMNAMAPK1CYP1A2 | |
| SCHEMBL3224251 | 0.81 | NPC1 (0.81) | POLBKDM4ELMNAMAPK1CYP1A2 | |
| SCHEMBL9856196 | 0.80 | POLB (0.76) | POLBKDM4ELMNAMAPK1CYP1A2 | |
| SCHEMBL7753048 | 0.80 | MAPK1 (0.58) | LMNAMAPK1CYP1A2CYP2C19HTT | |
| SCHEMBL9787076 | 0.79 | POLB (0.74) | POLBKDM4ELMNAMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197485-B1 | SUBSTANTIVE SKIN CARE COMPOSITIONS COMPRISING A POLYDIORGANOSILOXANE | DOW CORNING CORPORATION (US) | 1992-03-04 | — | — | EP | disclosed |
| EP-0197485-A2 | Substantive skin care compositions comprising a polydiorganosiloxane | DOW CORNING CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| US-4457910-A | WATER-INSOLUBLE NONIONIC SURFACTANT | ZARLEY, MCKEE, THOMTE, VOORHEES & SEASE (US) | 1984-07-03 | — | — | US | disclosed |
| US-4335104-A | TOPICAL COSMETIC OR INSECT REPELLENT | UNITED CHEMICAL CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| EP-0016203-A1 | ANHYDROUS MULTI-PURPOSE MOISTURIZING COMPOSITION | UNITED CHEMICAL CORPORATION (US) | 1980-10-01 | — | — | EP | disclosed |
| WO-1980000410-A1 | ANHYDROUS MULTI-PURPOSE MOISTURIZING COMPOSITION | UNITED CHEM CORP (US) | 1980-03-20 | — | — | WO | disclosed |