Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132415 | 0.82 | CYP3A4 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4084258 | 0.80 | PLA2G2A (0.44) | LMNAGAA | |
| SCHEMBL8773347 | 0.79 | CYP3A4 (0.39) | CYP3A4ADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL9836861 | 0.78 | CYP3A4 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8958844 | 0.78 | CYP3A4 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5139880 | 0.75 | — | — | |
| SCHEMBL3944907 | 0.74 | SMN1; SMN2 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9081577 | 0.74 | — | — | |
| SCHEMBL462082 | 0.73 | CYP3A4 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11182714 | 0.73 | PARP1 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303501-B1 | SULFUR DIOXIDE REMOVAL FROM GAS STREAMS USING SUBSTITUTED PIPERAZINONES | THE DOW CHEMICAL COMPANY (US) | 1992-05-13 | — | — | EP | disclosed |
| EP-0421794-A2 | Preparation of piperazinones for use as sulfur dioxide absorbents | THE DOW CHEMICAL COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4980471-A | Preparation of piperazinones for use as sulfur dioxide absorbents | THE DOW CHEMICAL COMPANY (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0303501-A2 | Sulfur dioxide removal from gas streams using substituted piperazinones | THE DOW CHEMICAL COMPANY (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4783327-A | Sulfur dioxide removal from gas streams using hydroxyalkyl substituted piperazinones | THE DOW CHEMICAL COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4767860-A | Preparation of N-substituted piperazinones | THE DOW CHEMICAL COMPANY (US) | 1988-08-30 | — | — | US | disclosed |