Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181713 | 0.74 | CA1 (0.53) | CA1CA2PTGS1 | |
| SCHEMBL9627290 | 0.69 | — | — | |
| SCHEMBL430924 | 0.61 | GABRA1 (0.58) | CA1CA2PTGS1MAPTSNCA | |
| SCHEMBL22322478 | 0.60 | MAPT (0.62) | MAPTSNCA | |
| SCHEMBL22624144 | 0.58 | ERN1 (0.37) | CA1CA2MAPT | |
| SCHEMBL28236194 | 0.56 | GABRA1 (0.60) | CA1CA2PTGS1MAPT | |
| SCHEMBL275427 | 0.55 | CA1 (1.00) | CA1CA2PTGS1MAPTSNCA | |
| SCHEMBL10197113 | 0.55 | — | — | |
| SCHEMBL6123591 | 0.55 | — | — | |
| SCHEMBL14308428 | 0.53 | ALDH1A1 (0.52) | CA1CA2MAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155122-A | Cyclooxygenase, lipoxygenase inhibitors | WARNER-LAMBERT COMPANY (US) | 1992-10-13 | — | — | US | claimed |