Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16110543 | 0.83 | OPRK1 (0.65) | OPRK1PDE4DKMT2AMEN1HPGD | |
| SCHEMBL9627340 | 0.81 | HPGD (0.66) | KMT2AMEN1HPGDLMNAALDH1A1 | |
| SCHEMBL30293257 | 0.76 | HPGD (0.50) | OPRK1PDE4DKMT2AMEN1HPGD | |
| SCHEMBL718072 | 0.75 | KMT2A (0.63) | KMT2AMEN1HPGDLMNAALDH1A1 | |
| SCHEMBL11431631 | 0.74 | OPRK1 (0.65) | OPRK1PDE4DKMT2AMEN1HPGD | |
| SCHEMBL11436899 | 0.74 | OPRK1 (0.61) | OPRK1PDE4DKMT2AMEN1HPGD | |
| SCHEMBL11433565 | 0.74 | OPRK1 (0.51) | OPRK1PDE4DKMT2AMEN1HPGD | |
| SCHEMBL6140528 | 0.74 | KMT2A (0.62) | KMT2AMEN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL10398760 | 0.74 | OPRK1 (0.65) | OPRK1PDE4DKMT2AMEN1HPGD | |
| SCHEMBL1184701 | 0.73 | KMT2A (0.56) | OPRK1PDE4DKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098901-A | Cardiovascular disorders | STERLING DRUG INC. (US) | 1992-03-24 | — | — | US | disclosed |