Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.43 |
| ▸ | TUBB | P07437 | 6/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628175 | 0.87 | HTT (0.46) | HTTABCB11TNFSF11TUBB4ATUBB | |
| SCHEMBL9627905 | 0.85 | TNFSF11 (0.45) | HTTTNFSF11NQO1AMY1ATSHR | |
| SCHEMBL9628542 | 0.85 | HTT (0.43) | HTTABCB11TSHRKDM4EALDH1A1 | |
| SCHEMBL9627541 | 0.84 | HTT (0.51) | HTTABCB11TNFSF11TUBB4ATUBB | |
| SCHEMBL9627729 | 0.84 | TUBB4A (0.54) | HTTABCB11TNFSF11TUBB4ATUBB | |
| SCHEMBL9629306 | 0.82 | ABCB11 (0.68) | HTTABCB11TNFSF11TUBB4ATUBB | |
| SCHEMBL9627790 | 0.82 | HTT (0.47) | HTTABCB11TNFSF11TUBB4ATUBB | |
| SCHEMBL9642607 | 0.81 | ABCB11 (0.67) | HTTABCB11TUBB4ATUBBTUBA3C | |
| SCHEMBL9627465 | 0.81 | HTT (0.69) | HTTABCB11TNFSF11TUBB4ATUBB | |
| SCHEMBL9627324 | 0.80 | HTT (0.44) | HTTABCB11TNFSF11TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |