Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625907 | 0.81 | IDO1 (0.34) | IDO1TAAR1IGF1RALOX15 | |
| SCHEMBL9625760 | 0.78 | CYP1A2 (0.41) | SIGMAR1 | |
| SCHEMBL9627460 | 0.77 | IDO1 (0.31) | IDO1 | |
| SCHEMBL9626044 | 0.75 | CALM1 (0.31) | ALOX15ALDH1A1 | |
| SCHEMBL9626169 | 0.74 | TAAR1 (0.39) | IDO1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9626222 | 0.73 | TAAR1 (0.37) | IDO1TAAR1NPC1ALDH1A1 | |
| SCHEMBL9626024 | 0.72 | TAAR1 (0.44) | IDO1TAAR1SIGMAR1ALDH1A1 | |
| SCHEMBL9478977 | 0.71 | AHR (0.30) | — | |
| SCHEMBL9626841 | 0.71 | MRGPRX4 (0.40) | — | |
| SCHEMBL11443994 | 0.70 | IGF1R (0.60) | IDO1PNMTTAAR1IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326297-B1 | THIOFORMAMIDE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1992-03-18 | — | — | EP | disclosed |
| US-4959385-A | MUSCLE RELAXANTS | MAY & BAKER LIMITED (GB) | 1990-09-25 | — | — | US | disclosed |
| EP-0326297-A1 | Thioformamide derivatives | MAY & BAKER LIMITED (GB) | 1989-08-02 | — | — | EP | disclosed |