Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333077 | 0.94 | CALM1 (0.32) | CALM1ALDH1A1ALOX15TDP1CES2 | |
| SCHEMBL9626222 | 0.90 | TAAR1 (0.37) | ALDH1A1HTT | |
| SCHEMBL9625907 | 0.83 | IDO1 (0.34) | ALOX15 | |
| SCHEMBL6503361 | 0.81 | CALM1 (0.41) | CALM1ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL9722607 | 0.80 | CYP2A6 (0.40) | TDP1 | |
| SCHEMBL9625760 | 0.80 | CYP1A2 (0.41) | — | |
| SCHEMBL9626169 | 0.80 | TAAR1 (0.39) | ALDH1A1 | |
| SCHEMBL5074193 | 0.79 | MAOA (0.31) | CALM1 | |
| SCHEMBL11223470 | 0.79 | DNM1 (0.43) | PKMHTTCES2CES1 | |
| SCHEMBL5074191 | 0.79 | DNM1 (0.43) | PKMHTTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326297-B1 | THIOFORMAMIDE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1992-03-18 | — | — | EP | disclosed |
| US-4959385-A | MUSCLE RELAXANTS | MAY & BAKER LIMITED (GB) | 1990-09-25 | — | — | US | disclosed |
| EP-0326297-A1 | Thioformamide derivatives | MAY & BAKER LIMITED (GB) | 1989-08-02 | — | — | EP | disclosed |