Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626044 | 0.83 | CALM1 (0.31) | ALOX15 | |
| SCHEMBL9627460 | 0.81 | IDO1 (0.31) | IDO1 | |
| SCHEMBL9626222 | 0.81 | TAAR1 (0.37) | IDO1TAAR1AGXT | |
| SCHEMBL9627477 | 0.81 | IDO1 (0.40) | IDO1TAAR1IGF1RALOX15 | |
| SCHEMBL196856 | 0.80 | IDO1 (0.46) | IDO1SLC6A4SLC6A2HTR2AHRH1 | |
| SCHEMBL10333077 | 0.77 | CALM1 (0.32) | IDO1SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL9625760 | 0.75 | CYP1A2 (0.41) | HTR2AHTR2B | |
| SCHEMBL5690887 | 0.71 | THRA (0.35) | SLC6A4SLC6A2HTR2ASLC6A3CHRM2 | |
| SCHEMBL3230192 | 0.71 | CNR1 (0.40) | HTR2ATAAR1MAOB | |
| SCHEMBL9722607 | 0.71 | CYP2A6 (0.40) | HRH1CHRNA4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326297-B1 | THIOFORMAMIDE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1992-03-18 | — | — | EP | disclosed |
| US-4959385-A | MUSCLE RELAXANTS | MAY & BAKER LIMITED (GB) | 1990-09-25 | — | — | US | disclosed |
| EP-0326297-A1 | Thioformamide derivatives | MAY & BAKER LIMITED (GB) | 1989-08-02 | — | — | EP | disclosed |