Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 8/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | ESRRG | P62508 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14393378 | 0.75 | KDM1A (0.50) | KDM1ALMNAESR1ESR2HSD17B10 | |
| SCHEMBL20017320 | 0.74 | KDM1A (0.54) | KDM1ALMNAESR1ESR2HSD17B10 | |
| SCHEMBL12873713 | 0.72 | KDM1A (0.76) | KDM1ALMNAESR1ESR2HSD17B10 | |
| SCHEMBL1187298 | 0.72 | KDM1A (0.76) | KDM1ALMNAESR1ESR2HSD17B10 | |
| SCHEMBL771386 | 0.72 | KDM1A (0.76) | KDM1ALMNAESR1ESR2HSD17B10 | |
| SCHEMBL22043774 | 0.70 | NOS3 (0.48) | KDM1ALMNAESR1ESR2HSD17B10 | |
| SCHEMBL14818169 | 0.68 | KDM1A (0.44) | KDM1ALMNAESR1ESR2HSD17B10 | |
| SCHEMBL4278135 | 0.64 | ESR1 (0.48) | LMNAESR1ESR2HSD17B10MAPT | |
| SCHEMBL22815269 | 0.64 | KDM1A (0.48) | KDM1ALMNAESR1ESR2HSD17B10 | |
| SCHEMBL129749 | 0.64 | ESR1 (0.50) | LMNAESR1ESR2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155122-A | Cyclooxygenase, lipoxygenase inhibitors | WARNER-LAMBERT COMPANY (US) | 1992-10-13 | — | — | US | disclosed |