Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493729 | 0.98 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9626558 | 0.98 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9626581 | 0.98 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9705145 | 0.96 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9706056 | 0.91 | ALDH1A1 (0.35) | ALDH1A1KMT2APOLB | |
| SCHEMBL822463 | 0.71 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9593176 | 0.70 | KMT2A (0.33) | ALDH1A1KMT2AHSD17B10MAPTALOX15 | |
| SCHEMBL1072615 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL4267972 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL10261468 | 0.70 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011646-A1 | THERMOPLASTIC NORBORNENE DICARBOXIMIDE POLYMERS USEFUL FOR DIELECTRIC DEVICES | MONSANTO COMPANY (US) | 1992-07-09 | — | — | WO | claimed |
| EP-0491672-A2 | Hydrogenated cyclic alkyl polymers | MONSANTO COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |
| US-5115037-A | Hydrogenated metathesis ring-opening polymerization of norbornene dicarboximide polymers resulting in ethylene cyclopentae dicarboximide polymers | MONSANTO COMPANY (US) | 1992-05-19 | — | — | US | disclosed |