SCHEMBL9593176

SCHEMBL9593176

CN1C(=O)C2=C(C1=O)C1CCC2C1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
YTHDF2 Q9Y5A9 1/20 0.31
PTGS2 P35354 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23034915 0.81 ALDH1A1 (0.37) KMT2AMEN1ALDH1A1MAPTALOX15
SCHEMBL27630310 0.78 ALDH1A1 (0.38) KMT2AALDH1A1HSD17B10
SCHEMBL1072615 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL4267972 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL12856046 0.74 ALDH1A1 (0.38) KMT2AYTHDF2ALDH1A1
SCHEMBL20827191 0.72 ALDH1A1 (0.36) KMT2AYTHDF2ALDH1A1
SCHEMBL9705145 0.70 ALDH1A1 (0.38) KMT2AALDH1A1MAPTALOX15HSD17B10
SCHEMBL9628044 0.70 ALDH1A1 (0.41) KMT2AALDH1A1MAPTALOX15HSD17B10
SCHEMBL7347918 0.69 SLC6A3 (0.33)
SCHEMBL9626558 0.69 ALDH1A1 (0.44) KMT2AALDH1A1MAPTALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130228901-A1 MATERIALS AND METHODS FOR STRESS REDUCTION IN SEMICONDUCTOR WAFER PASSIVATION LAYERS DESIGNER MOLECULES, INC. (US) 2013-09-05 US disclosed
WO-1993006171-A1 POLYMER BLENDS OF NORBORNENE DICARBOXIMIDES MONSANTO COMPANY (US) 1993-04-01 WO disclosed
WO-1992011646-A1 THERMOPLASTIC NORBORNENE DICARBOXIMIDE POLYMERS USEFUL FOR DIELECTRIC DEVICES MONSANTO COMPANY (US) 1992-07-09 WO disclosed