Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072615 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TDP1ELANE | |
| SCHEMBL9593176 | 0.75 | KMT2A (0.33) | ALDH1A1 | |
| SCHEMBL9628044 | 0.70 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL9705145 | 0.70 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL7347918 | 0.69 | SLC6A3 (0.33) | ELANE | |
| SCHEMBL9493729 | 0.69 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL9626558 | 0.69 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL9626581 | 0.69 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL2077444 | 0.66 | CASP3 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL12583840 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014081299-A1 | ACTIVATABLE LIPOSOMES | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2014-05-30 | — | — | WO | disclosed |
| US-7608687-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2009-10-27 | — | — | US | disclosed |
| US-7592307-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| US-20080279922-A1 | Releasable linkage and compositions containing same | ALZA CORPORATION | 2008-11-13 | — | — | US | disclosed |
| US-20080152702-A1 | Releasable linkage and compositions containing same | ZALIPSKY SAMUEL | 2008-06-26 | — | — | US | disclosed |
| US-7390780-B2 | Gene delivery mediated by liposome-DNA complex with cleavable peg surface modification | ALZA CORPORATION (US) | 2008-06-24 | — | — | US | disclosed |
| EP-1880736-A1 | Releasable linkage and composition containing same | Alza Corporation (US) | 2008-01-23 | — | — | EP | disclosed |
| US-7285622-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2007-10-23 | — | — | US | disclosed |
| US-7238368-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7112337-B2 | Liposome composition for delivery of nucleic acid | ALZA CORPORATION (US) | 2006-09-26 | — | — | US | disclosed |
| US-20020172711-A1 | Therapeutic liposome composition and method of preparation | ALZA CORPORATION | 2002-11-21 | — | — | US | disclosed |
| US-20020128195-A1 | Releasable linkage and compositions containing same | ALZA CORPORATION | 2002-09-12 | — | — | US | disclosed |
| EP-1214935-A2 | Fusogenic liposome composition and method | SEQUUS PHARMACEUTICALS, INC. (US) | 2002-06-19 | — | — | EP | disclosed |
| US-6342244-B1 | HYDROPHILIC POLYMER COVALENTLY YET REVERSIBLY LINKED TO A AMINE-CONTAINING LIGAND THROUGH A DITHIOBENZYL LINKAGE; MODIFICATION OF VARIOUS SUBSTRATES, SUCH AS POLYPEPTIDES, DRUGS AND LIPOSOMES; UPON CLEAVAGE OF THE LINKAGE, THE LIGAND | ALZA CORPORATION | 2002-01-29 | — | — | US | disclosed |
| EP-1173221-A2 | RELEASABLE LINKAGE AND COMPOSITIONS CONTAINING SAME | Alza Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| US-6224903-B1 | HYDROPHILIC-HYDROPHOBIC POLYMERS | SEQUUS PHARMACEUTICALS, INC. | 2001-05-01 | — | — | US | disclosed |
| WO-2000064483-A2 | RELEASABLE LINKAGE AND COMPOSITIONS CONTAINING SAME | ALZA CORPORATION (US) | 2000-11-02 | — | — | WO | disclosed |
| EP-0932391-A2 | FUSOGENIC LIPOSOME COMPOSITION AND METHOD | SEQUUS PHARMACEUTICALS, INC. (US) | 1999-08-04 | — | — | EP | disclosed |
| US-5891468-A | DRUG DELIVERY | SEQUUS PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| WO-1998016202-A2 | FUSOGENIC LIPOSOME COMPOSITION AND METHOD | SEQUUS PHARMACEUTICALS, INC. (US) | 1998-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128195-A1 | Releasable linkage and compositions containing same | CD44, ILK, CD69 | ALDH1A1 1574/4885TDP1 378/4885ELANE 209/4885 |
| US-20080279922-A1 | Releasable linkage and compositions containing same | CD44, SHMT1, HCAR1 | ALDH1A1 718/4885TDP1 603/4885ELANE 620/4885 |
| US-20080152702-A1 | Releasable linkage and compositions containing same | CD44, ILK, CD69 | ALDH1A1 1574/4885TDP1 378/4885ELANE 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.