Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203388 | 0.83 | TSHR (0.67) | TSHRLMNAALDH1A1TDP1CHRNB2 | |
| SCHEMBL6273333 | 0.82 | TSHR (0.64) | TSHRLMNAALDH1A1TDP1CHRNB2 | |
| SCHEMBL30043252 | 0.82 | TSHR (0.64) | TSHRLMNAALDH1A1TDP1CHRNB2 | |
| SCHEMBL28940575 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1CHRNB2 | |
| SCHEMBL10948730 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1CHRNB2 | |
| SCHEMBL535532 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1CHRNB2 | |
| SCHEMBL30059246 | 0.80 | LMNA (0.61) | TSHRLMNAALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL5609078 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1CHRNB2 | |
| SCHEMBL9158141 | 0.80 | ALDH1A1 (0.67) | TSHRLMNAALDH1A1TDP1CHRNB2 | |
| SCHEMBL515302 | 0.80 | LMNA (0.61) | TSHRLMNAALDH1A1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081296-A | Fiber-Reactive Dyes Intermediates | CIBA-GEIGY CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |