Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626552 | 0.82 | ACHE (0.44) | CYP19A1MAOBMAPTMEN1KMT2A | |
| SCHEMBL9525132 | 0.76 | CYP19A1 (0.51) | CYP19A1MAOBITGA4ITGB7MAPT | |
| SCHEMBL9629885 | 0.76 | PDK1 (0.34) | MAOBMAPTMEN1KMT2AACHE | |
| SCHEMBL9626473 | 0.76 | MEN1 (0.36) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9627102 | 0.74 | CYP19A1 (0.50) | CYP19A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3017594 | 0.72 | MEN1 (0.65) | CYP19A1MAOBITGA4ITGB7MAPT | |
| SCHEMBL9626541 | 0.72 | ITGA4 (0.47) | CYP19A1MAOBITGA4ITGB7MAPT | |
| SCHEMBL5733771 | 0.71 | MEN1 (0.36) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27587741 | 0.71 | CYP19A1 (0.51) | CYP19A1MAOBITGA4ITGB7MAPT | |
| SCHEMBL5736112 | 0.71 | HSP90AA1 (0.36) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145483-A | Hair dyes | L'OREAL (FR) | 1992-09-08 | — | — | US | disclosed |