Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.40 |
| ▸ | CKS1B | P61024 | 7/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 7/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753630 | 0.97 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL3369301 | 0.97 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL5694613 | 0.97 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| Potassium Ion SCHEMBL5694612 | 0.97 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| Lithium Ion SCHEMBL5694584 | 0.97 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL8143771 | 0.96 | GLO1 (0.39) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL10979738 | 0.96 | GLO1 (0.39) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL2392734 | 0.85 | TOP2A (0.43) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL21240720 | 0.79 | CKS1B (0.47) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL1226790 | 0.77 | TOP1 (0.53) | TOP2AIKBKBCHUKDAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459356-A | Radioactive staining of gels to identify proteins | GEORGETOWN UNIVERSITY (US) | 1984-07-10 | — | — | US | claimed |
| US-5101020-A | Novel radio labeled dyes for detecting proteins in gels | LINUS PAULING INSTITUTE OF SCIENCE AND MEDICINE (US) | 1992-03-31 | — | — | US | disclosed |
| US-4966854-A | Radio labelled dye composition for detecting proteins in gels | LINUS PAULING INSTITUTE OF SCIENCE AND MEDICINE (US) | 1990-10-30 | — | — | US | disclosed |
| US-4769334-A | Method for detecting proteins in gels using radioactive dyes | LINUS PAULING INSTITUTE OF SCIENCE AND MEDICINE (US) | 1988-09-06 | — | — | US | disclosed |
| US-4459356-A | Radioactive staining of gels to identify proteins | GEORGETOWN UNIVERSITY (US) | 1984-07-10 | — | — | US | disclosed |
| US-4459356-A | Radioactive staining of gels to identify proteins | GEORGETOWN UNIVERSITY (US) | 1984-07-10 | — | — | US | disclosed |