Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A known ✓ | Q15858 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.40 |
| ▸ | CKS1B | P61024 | 7/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 7/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753630 | 1.00 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL8143771 | 0.99 | GLO1 (0.39) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL5694613 | 0.97 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL9628172 | 0.97 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| Lithium Ion SCHEMBL5694584 | 0.97 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| Potassium Ion SCHEMBL5694612 | 0.97 | GLO1 (0.40) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL10979738 | 0.96 | GLO1 (0.39) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL2392734 | 0.85 | TOP2A (0.43) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL93351 | 0.78 | CKS1B (0.37) | GLO1CKS1BSKP2TOP2AMMP2 | |
| SCHEMBL1226790 | 0.77 | TOP1 (0.53) | TOP2AIKBKBCHUKDAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895713-B2 | Polyelectrolyte multilayers having salt-controlled internal structures | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896593-B2 | Polyelectrolyte multilayers having salt-controlled internal structures | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2018-02-20 | — | — | US | disclosed |
| US-20140242376-A1 | POLYELECTROLYTE MULTILAYERS HAVING SALT-CONTROLLED INTERNAL STRUCTURES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140193644-A1 | POLYELECTROLYTE MULTILAYERS HAVING SALT-CONTROLLED INTERNAL STRUCTURES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-07-10 | — | — | US | disclosed |
| EP-1942195-B1 | Colorimetric method and reagent used for the same | ARKRAY INC (JP) | 2010-09-22 | — | — | EP | disclosed |
| EP-1457572-B1 | METHOD OF COLORIMETRY AND REAGENT FOR USE THEREIN | ARKRAY INC (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-1466987-B1 | METHOD OF COLORIMETRY | ARKRAY INC (JP) | 2008-11-19 | — | — | EP | disclosed |
| EP-1942195-A1 | Colorimetric method and reagent used for the same | Arkray, Inc. (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-1466987-A1 | METHOD OF COLORIMETRY AND REAGENT FOR USE THEREIN | ARKRAY, Inc. (JP) | 2004-10-13 | — | — | EP | disclosed |
| EP-1457572-A1 | METHOD OF COLORIMETRY AND REAGENT FOR USE THEREIN | ARKRAY, Inc. (JP) | 2004-09-15 | — | — | EP | disclosed |
| JP-2000023695-A | TREATMENT OF SPECIMEN | KDK CORP | 2000-01-25 | — | — | JP | disclosed |