Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANTXR2 | P58335 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SI | P14410 | 3/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659115 | 0.80 | PDE4D (0.40) | SMN1; SMN2GAAABCB1KDM4EMAPT | |
| SCHEMBL9628341 | 0.80 | EP300 (0.53) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL9628299 | 0.79 | EP300 (0.44) | MGAMGAASIMGAM2ABCB1 | |
| SCHEMBL9659075 | 0.78 | ALDH1A1 (0.44) | SMN1; SMN2GAAMAPK1ABCB1KDM4E | |
| SCHEMBL9627887 | 0.77 | PPARG (0.42) | ANTXR2SMN1; SMN2PPARGMAPK1KDM4E | |
| SCHEMBL10628942 | 0.76 | PDE4D (0.41) | KDM4EHPGDL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL9654692 | 0.75 | PPARG (0.46) | ANTXR2CTSVPPARGMAPK1KDM4E | |
| SCHEMBL9627702 | 0.75 | CTSV (0.40) | ANTXR2CTSVGAAPPARGMAPK1 | |
| SCHEMBL12627553 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPK1LMNAMAPTHPGD | |
| SCHEMBL9656300 | 0.74 | MAPT (0.53) | ANTXR2CTSVGAAPPARGMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |