Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MGAM | O43451 | 3/20 | 0.44 |
| ▸ | SI | P14410 | 3/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628299 | 0.90 | EP300 (0.44) | EP300GAAMGAMSIMGAM2 | |
| SCHEMBL9628240 | 0.87 | EP300 (0.56) | EP300GAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9627467 | 0.84 | TUBB4A (0.45) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL9628286 | 0.81 | EP300 (0.65) | EP300GAASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9627600 | 0.80 | MEN1 (0.46) | EP300HTTMEN1KMT2AMAPT | |
| SCHEMBL9629502 | 0.80 | MEN1 (0.46) | EP300HTTMEN1KMT2AMAPT | |
| SCHEMBL9628233 | 0.80 | ANTXR2 (0.44) | EP300GAAMGAMSIMGAM2 | |
| SCHEMBL9657777 | 0.79 | LMNA (0.47) | EP300GAAALDH1A1HTTMEN1 | |
| SCHEMBL9628323 | 0.79 | HTT (0.54) | GAASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL9627686 | 0.78 | SLC2A1 (0.46) | EP300SMN1; SMN2ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |