SCHEMBL9628329

SCHEMBL9628329

COC1=C(C)C(=O)c2cccc(OC)c2C1=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
MAPT P10636 4/20 0.60
CDC25A P30304 1/20 0.60
CDC25B P30305 1/20 0.60
APAF1 O14727 1/20 0.60
MITF O75030 1/20 0.60
LMNA P02545 1/20 0.60
HTT P42858 1/20 0.60
EGFR P00533 1/20 0.60
PIM1 P11309 1/20 0.60
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
KDM4E B2RXH2 1/20 0.58
USP2 O75604 1/20 0.58
DUSP3 P51452 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
ELANE P08246 3/20 0.58
RAB9A P51151 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
TOP1 P11387 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23271965 0.91 ALDH1A1 (0.62) ALDH1A1MAPTCDC25ACDC25BAPAF1
SCHEMBL30003387 0.91 ALDH1A1 (0.62) ALDH1A1MAPTCDC25ACDC25BAPAF1
SCHEMBL5816933 0.89 EGFR (0.64) ALDH1A1MAPTCDC25ACDC25BAPAF1
SCHEMBL3417492 0.86 EGFR (0.76) ALDH1A1MAPTAPAF1MITFLMNA
SCHEMBL10974170 0.85 EGFR (0.74) ALDH1A1MAPTAPAF1MITFLMNA
SCHEMBL30003168 0.84 EGFR (0.64) ALDH1A1MAPTAPAF1MITFLMNA
SCHEMBL9628316 0.84 MAPT (0.55) ALDH1A1MAPTCDC25ACDC25BAPAF1
SCHEMBL23271858 0.84 EGFR (0.64) ALDH1A1MAPTAPAF1MITFLMNA
SCHEMBL8947495 0.84 EGFR (0.73) ALDH1A1MAPTAPAF1MITFLMNA
SCHEMBL9628613 0.83 CDC25A (0.62) ALDH1A1MAPTCDC25ACDC25BAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112209814-B Novel method for synthesizing vitamin K2 黄冈鲁班药业股份有限公司 2023-05-26 CN disclosed
CN-112209814-A Novel method for synthesizing vitamin K2 黄冈鲁班药业股份有限公司 2021-01-12 CN disclosed
US-5155132-A Nonsteroidal antiinflammatory agents; treating psoriasis SYNTEX (U.S.A.) INC. (US) 1992-10-13 US disclosed
US-5134161-A Enzyme inhibitors for skin disorders, antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-07-28 US disclosed
US-5089657-A Topical antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-02-18 US disclosed
US-4786652-A TOPICAL ADMINISTRATION SYNTEX (U.S.A.) INC. (US) 1988-11-22 US disclosed
EP-0282006-A1 Naphtalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
EP-0282056-A2 Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
US-4758587-A Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-07-19 US disclosed