SCHEMBL9628403

SCHEMBL9628403

CCOC(C)OCC.COc1cc(OC)nc(Oc2cccnc2C=O)n1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSA P10619 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9629432 0.89 CTSA (0.41) CTSASMN1; SMN2NPSR1CYP1A2CYP3A4
SCHEMBL9383414 0.88 NPSR1 (0.44) CTSASMN1; SMN2NPSR1CYP1A2CYP3A4
SCHEMBL9629396 0.86 LMNA (0.38) SMN1; SMN2
SCHEMBL9475263 0.83 NPSR1 (0.44) SMN1; SMN2NPSR1CYP1A2CYP3A4CYP2C9
SCHEMBL9627638 0.83 CTSA (0.46) CTSANPSR1
SCHEMBL9383727 0.81 ALDH1A1 (0.44) SMN1; SMN2
SCHEMBL9628410 0.76 SMN1; SMN2 (0.44) CTSASMN1; SMN2NPSR1
SCHEMBL9618662 0.73 SMN1; SMN2 (0.43) CTSASMN1; SMN2NPSR1
SCHEMBL9618663 0.73 SMN1; SMN2 (0.43) CTSASMN1; SMN2NPSR1
SCHEMBL9732803 0.72 ALDH1A1 (0.57) SMN1; SMN2NPSR1CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5129937-A Pre- and postemergence; soybean, cotton, corn; injury free MITSUI TOATSU CHEMICALS INCORPORATED (JP) 1992-07-14 US disclosed
EP-0435186-A2 Pyridyloxypyrimidine derivatives, preparation process thereof, and herbicidal compositions containing the same as active ingredients MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-07-03 EP disclosed