Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628403 | 0.86 | CTSA (0.41) | SMN1; SMN2 | |
| SCHEMBL9627618 | 0.79 | ALDH1A1 (0.36) | LMNAALDH1A1KDM4EMEN1HTT | |
| SCHEMBL934218 | 0.76 | GRM5 (0.45) | LMNAALDH1A1MEN1HTTKMT2A | |
| SCHEMBL8752083 | 0.73 | LMNA (0.44) | LMNAALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL9629432 | 0.72 | CTSA (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL933809 | 0.71 | MEN1 (0.43) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL24323463 | 0.70 | NFE2L2 (0.40) | ALDH1A1SMN1; SMN2HTTNFE2L2NPC1 | |
| SCHEMBL871658 | 0.70 | GRM5 (0.43) | LMNAALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL29601108 | 0.70 | NFE2L2 (0.40) | ALDH1A1SMN1; SMN2HTTNFE2L2NPC1 | |
| SCHEMBL1536639 | 0.70 | NCF1 (0.43) | LMNAALDH1A1KDM4ESMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435186-A2 | Pyridyloxypyrimidine derivatives, preparation process thereof, and herbicidal compositions containing the same as active ingredients | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-07-03 | — | — | EP | claimed |
| US-5129937-A | Pre- and postemergence; soybean, cotton, corn; injury free | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0435186-A2 | Pyridyloxypyrimidine derivatives, preparation process thereof, and herbicidal compositions containing the same as active ingredients | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-07-03 | — | — | EP | disclosed |