Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | CEL | P19835 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627446 | 0.98 | HTR2C (0.44) | HTR2CCELTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9912424 | 0.92 | HTR2C (0.48) | HTR2CTAS1R3TAS1R1TAS1R2OPRL1 | |
| SCHEMBL3792040 | 0.85 | CEL (0.48) | HTR2CCELOPRL1HTR1AHTR7 | |
| SCHEMBL3783301 | 0.83 | CEL (0.50) | CELOPRL1HTR1AHTR7PTGS2 | |
| SCHEMBL3789549 | 0.81 | CEL (0.44) | HTR2CCELOPRL1HTR1AHTR7 | |
| SCHEMBL466853 | 0.80 | ALDH1A1 (0.50) | HTR2CTAS1R3TAS1R1TAS1R2HTR1A | |
| SCHEMBL6386133 | 0.79 | HTR2C (0.69) | HTR2CTAS1R3TAS1R1TAS1R2HTR1A | |
| SCHEMBL31469392 | 0.79 | HTR2C (0.67) | HTR2COPRL1PTGS2 | |
| SCHEMBL43079 | 0.79 | HTR2C (0.67) | HTR2COPRL1PTGS2 | |
| SCHEMBL8954630 | 0.78 | ALDH1A1 (0.48) | HTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347690-B1 | PROCESS FOR MANUFACTURING BENZENE DERIVATIVES, AND BENZENE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-10-21 | — | — | EP | disclosed |
| US-5151548-A | Crop protection agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-29 | — | — | US | disclosed |
| EP-0347690-A2 | Process for manufacturing benzene derivatives, and benzene derivatives | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |