SCHEMBL466853

SCHEMBL466853

Cc1cccc(C2CCCC2)c1O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
HTR2C P28335 4/20 0.46
TRPA1 O75762 1/20 0.45
FEN1 P39748 4/20 0.40
PTPN5 P54829 3/20 0.40
ALOX5AP P20292 3/20 0.40
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
PTPN2 P17706 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HTR1A P08908 1/20 0.38
HTR7 P34969 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
TAS1R2 Q8TE23 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673222 0.98 ALDH1A1 (0.48) ALDH1A1HTR2CTRPA1FEN1PTPN5
SCHEMBL30218222 0.98 ALDH1A1 (0.48) ALDH1A1HTR2CTRPA1FEN1PTPN5
SCHEMBL8954630 0.98 ALDH1A1 (0.48) ALDH1A1HTR2CTRPA1FEN1PTPN5
Methane SCHEMBL9104929 0.96 ALDH1A1 (0.46) ALDH1A1HTR2CTRPA1FEN1PTPN5
SCHEMBL930208 0.92 ALDH1A1 (0.54) ALDH1A1HTR2CTRPA1GABRA1GABRB2
SCHEMBL20036789 0.86 ALDH1A1 (0.41) ALDH1A1HTR2CTRPA1FEN1PTPN5
SCHEMBL4960831 0.85 PTPN5 (0.44) FEN1PTPN5ALOX5APPTPN2KDM4E
SCHEMBL23854308 0.84 ADRA2A (0.41) ALDH1A1HTR2CTRPA1FEN1PTPN5
SCHEMBL4960398 0.83 PTPN5 (0.46) FEN1PTPN5ALOX5APPTPN2KDM4E
SCHEMBL4959318 0.83 PTPN5 (0.46) FEN1PTPN5ALOX5APPTPN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101541859-A Poly (arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP (NL) 2009-09-23 CN claimed
US-20080076884-A1 POLY(ARYLENE ETHER) COMPOSITION AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-27 US claimed
WO-2008036454-A1 POLY (ARYLENE ETHER) COPOLYMER SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-03-27 WO claimed
EP-3006543-B1 POLYFUNCTIONAL LUBRICANT COMPOSITION ADEKA CORP (JP) 2021-05-26 EP disclosed
US-9738848-B2 Polyfunctional lubricant composition ADEKA CORPORATION (JP) 2017-08-22 US disclosed
US-20160122679-A1 POLYFUNCTIONAL LUBRICANT COMPOSITION ADEKA CORPORATION (JP) 2016-05-05 US disclosed
EP-3006543-A1 POLYFUNCTIONAL LUBRICANT COMPOSITION Adeka Corporation (JP) 2016-04-13 EP disclosed
US-8410184-B2 Regeneration of acidic ion exchangers BAYER MATERIALSCIENCE AG (DE) 2013-04-02 US disclosed
EP-2263794-B1 Regeneration of acid ion exchangers BAYER MATERIALSCIENCE AG (DE) 2012-03-28 EP disclosed
CN-102380243-A Apparatus and method for solid/liquid separation of solid-liquid suspensions BAYER MATERIALSCIENCE AG 2012-03-21 CN disclosed
US-20120010433-A1 DEVICE AND PROCESS FOR SOLID/LIQUID SEPARATION OF SOLID-LIQUID SUSPENSIONS BAYER MATERIALSCIENCE AG (DE) 2012-01-12 US disclosed
WO-1999032423-A1 METHOD FOR PRODUCING BIS(4-HYDROXYARYL)ALKANES BAYER AKTIENGESELLSCHAFT (DE) 1999-07-01 WO disclosed
WO-1998052897-A1 METHOD FOR PROCESSING MOTHER LIQUORS FROM THE PRODUCTION OF BISPHENOL BAYER AKTIENGESELLSCHAFT (DE) 1998-11-26 WO disclosed
WO-1998052895-A1 METHOD FOR CONTINUOUS PRODUCTION OF DIHYDROXYDIARYLALKANES BAYER AKTIENGESELLSCHAFT (DE) 1998-11-26 WO disclosed
WO-1998031651-A1 PROCESS FOR PREPARING BIS-(4-HYDROXYARYL-)-ALKANES BAYER AKTIENGESELLSCHAFT (DE) 1998-07-23 WO disclosed
EP-0754666-A2 Process for the preparation of bis-(4-hydroxyaryl)alcanes BAYER AG (DE) 1997-01-22 EP disclosed
EP-0347690-B1 PROCESS FOR MANUFACTURING BENZENE DERIVATIVES, AND BENZENE DERIVATIVES BASF Aktiengesellschaft (DE) 1992-10-21 EP disclosed
US-5151548-A Crop protection agents BASF AKTIENGESELLSCHAFT (DE) 1992-09-29 US disclosed
EP-0347690-A2 Process for manufacturing benzene derivatives, and benzene derivatives BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4115355-A SUBSTITUTED PHENOLS NIPPON ZEON CO. LTD. (JP) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010433-A1 DEVICE AND PROCESS FOR SOLID/LIQUID SEPARATION OF SOLID-LIQUID SUSPENSIONS SORD, SLFN12, MCM5 ALDH1A1 4274/4885HTR2C 4186/4885TRPA1 1546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.