SCHEMBL9628592

SCHEMBL9628592

CS(=N)(=O)c1ccc(C#N)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.52
CA1 P00915 5/20 0.52
CA9 Q16790 4/20 0.52
CA12 O43570 3/20 0.52
PTGS2 P35354 1/20 0.50
BCHE P06276 1/20 0.47
ACHE P22303 1/20 0.47
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
CYP19A1 P11511 1/20 0.46
ALDH1A1 P00352 1/20 0.44
CYP2A6 P11509 1/20 0.44
CA3 P07451 1/20 0.44
CA6 P23280 1/20 0.44
CA14 Q9ULX7 1/20 0.44
KDM1A O60341 1/20 0.42
IDO1 P14902 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL803901 0.82 PTGS2 (0.68) CA2CA1CA9CA12PTGS2
SCHEMBL1332778 0.79 CA2 (0.57) CA2CA1CA9CA12PTGS2
SCHEMBL25619887 0.78 CA1 (0.47) CA2CA1CA9CA12PTGS2
SCHEMBL4190362 0.77 PTGS2 (0.72) CA2CA1CA9CA12PTGS2
SCHEMBL8514633 0.77 CA2 (0.59) CA2CA1CA9CA12PTGS2
SCHEMBL1894003 0.75 CA2 (0.57) CA2CA1CA9CA12PTGS2
SCHEMBL506270 0.74 MAPT (0.55) CA2CA1CA9CA12PTGS2
SCHEMBL13623391 0.74 CYP19A1 (0.54) CA2CA1CA9CA12PTGS2
SCHEMBL13363525 0.74 EPAS1 (0.49) CA2CA1CA9CA12PTGS2
SCHEMBL8779787 0.73 CA2 (0.55) CA2CA1CA9CA12PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233865-A1 ENPP1 INHIBITORS RE VENTURES I, LLC (US) 2025-11-13 WO disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
WO-2025073057-A1 METHODS FOR PREPARING SULFILIMINES AND SULFOXIMINES FROM THIOETHERS USING O-(DIPHENYLPHOSPHINYL)HYDROXYL AMINE (DPPH), AND AMATOXIN ANALOGS PREPARED FROM SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2025-04-10 WO disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
US-20220169621-A1 OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2022-06-02 US disclosed
US-20220169621-A1 OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2022-06-02 US disclosed
US-11286242-B2 Oxadiazoles for use in controlling phytopathogenic fungi PI INDUSTRIES LTD. (IN) 2022-03-29 US disclosed
EP-3746439-A2 OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI PI Industries Ltd. (IN) 2020-12-09 EP disclosed
US-20200354326-A1 OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2020-11-12 US disclosed
US-20200354326-A1 OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2020-11-12 US disclosed
WO-2019150219-A9 OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2019-11-28 WO disclosed
WO-2019150219-A9 OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2019-11-28 WO disclosed
WO-2019150219-A2 NOVEL OXADIAZOLES PI INDUSTRIES LTD. (IN) 2019-08-08 WO disclosed
WO-2019150219-A2 NOVEL OXADIAZOLES PI INDUSTRIES LTD. (IN) 2019-08-08 WO disclosed
WO-2018030550-A1 HETEROCYCLIC COMPOUNDS WITH AN ROR(GAMMA)T MODULATING ACTIVITY TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-02-15 WO disclosed
US-5140026-A N-aminoalkyl-S-aryl-S-alkyl (or substituted alkyl) sulfoximines as antiarrhythmic agents A. H. ROBINS COMPANY, INCORPORATED (US) 1992-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286242-B2 Oxadiazoles for use in controlling phytopathogenic fungi OXA1L, CYP51A1, CYP1A1 CA2 2964/4885CA1 3515/4885CA9 3251/4885
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS CA2 3902/4885CA1 4801/4885CA9 4604/4885
US-20200354326-A1 OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI OXA1L, CYP51A1, CYP1A1 CA2 2964/4885CA1 3515/4885CA9 3251/4885
US-20220169621-A1 OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI OXA1L, CYP51A1, CYP1A1 CA2 2964/4885CA1 3515/4885CA9 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.