Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853783 | 0.90 | TP53 (0.49) | KMT2AMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL9629579 | 0.81 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL9628745 | 0.76 | KMT2A (0.46) | KMT2AMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL9629602 | 0.75 | KMT2A (0.53) | KMT2AMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL9630780 | 0.72 | SMN1; SMN2 (0.33) | MAPTHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL12902087 | 0.69 | MEN1 (0.42) | KMT2AMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL5636523 | 0.68 | NPC1 (0.44) | KMT2ATP53EPHX2CRBNLMNA | |
| SCHEMBL9629535 | 0.66 | CRBN (0.35) | EPHX2CRBNMMP12ALDH1A1SMN1; SMN2 | |
| SCHEMBL9215866 | 0.66 | CA12 (0.46) | KMT2AMEN1TP53MAPTCA12 | |
| SCHEMBL8853758 | 0.65 | LMNA (0.54) | KMT2AMEN1TSHRCYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |