Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853758 | 0.89 | LMNA (0.54) | KMT2AMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL9629602 | 0.82 | KMT2A (0.53) | KMT2AMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL14433978 | 0.78 | EPHX2 (0.62) | KMT2AMEN1RAB9ALMNAEPHX2 | |
| SCHEMBL9628734 | 0.76 | KMT2A (0.43) | KMT2AMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL9629681 | 0.76 | KMT2A (0.49) | KMT2AMEN1LMNATP53HDAC1 | |
| SCHEMBL9629595 | 0.76 | HDAC1 (0.48) | KMT2AMEN1CYP2C19LMNATP53 | |
| SCHEMBL9628766 | 0.75 | MAOA (0.55) | KMT2ALMNATP53HDAC1HDAC8 | |
| SCHEMBL9628996 | 0.74 | MAPT (0.53) | KMT2AMEN1TSHRCYP2C19RAB9A | |
| SCHEMBL9629644 | 0.73 | MAOB (0.68) | KMT2AMEN1LMNAEPHX2MAPT | |
| SCHEMBL9629024 | 0.72 | KIF11 (0.47) | HDAC1HDAC8HDAC6MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |