Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 7/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1130077 | 0.90 | MCL1 (0.64) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL39206 | 0.84 | KMT2A (1.00) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL15227812 | 0.84 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL264702 | 0.82 | ALDH1A1 (0.85) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL3854600 | 0.81 | KMT2A (0.70) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL10780555 | 0.80 | KMT2A (0.85) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL267885 | 0.80 | ALDH1A1 (1.00) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL30009645 | 0.80 | KMT2A (0.72) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11067738 | 0.80 | KMT2A (0.72) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL29570529 | 0.80 | KMT2A (0.72) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166350-A | Process for the manufacture of fluoran compounds | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-4806657-A | REACTING KETON ACID WITH 4-FORMYLAMINOPHENOL; DECARBONYLATION, CYCLIZATION AND CONDENSATION | CIBA-GEIGY CORPORATION (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0089752-B1 | FLUORAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN RECORDING SYSTEMS | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1988-04-20 | — | — | EP | disclosed |
| US-4524373-A | Fluoran derivatives as new compounds, process for preparing the same and recording system utilizing the same as colorless chromogenic material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1985-06-18 | — | — | US | disclosed |
| EP-0089752-A2 | Fluoran derivatives, process for their preparation and their use in recording systems | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1983-09-28 | — | — | EP | disclosed |