SCHEMBL3854600

SCHEMBL3854600

C=CCN(CC=C)c1ccc(C(=O)c2ccccc2C(=O)O)c(O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.70
▸ MEN1 O00255 4/20 0.70
▸ SMN1; SMN2 Q16637 1/20 0.70
▸ L3MBTL1 Q9Y468 1/20 0.70
▸ ALDH1A1 P00352 4/20 0.64
▸ GAA P10253 2/20 0.64
▸ KDM4E B2RXH2 1/20 0.64
▸ POLB P06746 1/20 0.64
▸ RECQL P46063 1/20 0.42
▸ CDC25B P30305 3/20 0.41
▸ CDC25A P30304 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ MCL1 Q07820 2/20 0.40
▸ BCL2L1 Q07817 1/20 0.40
▸ HPGD P15428 2/20 0.39
▸ EGFR P00533 1/20 0.39
▸ LCK P06239 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ CYP3A4 P08684 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10869821 0.91 MEN1 (0.57) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL9754652 0.89 ALDH1A1 (0.81) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL16340374 0.85 MEN1 (0.54) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL6441612 0.84 CYP3A4 (0.56) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL39206 0.82 KMT2A (1.00) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL11525076 0.81 MEN1 (0.42) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL9628778 0.81 MEN1 (0.73) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL11399468 0.81 AKR1C3 (0.54) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL29570529 0.80 KMT2A (0.72) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL6205557 0.80 KMT2A (0.72) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160152554-A1 METHOD FOR PRODUCING 2-(4-N,N-DIALKYLAMINO-2-HYDROXYBENZOYL) BENZOATES DSM IP ASSETS B.V. (NL) 2016-06-02 — — US claimed
EP-3013788-A1 METHOD FOR PRODUCING 2-(4-N,N-DIALKYLAMINO-2-HYDROXYBENZOYL) BENZOATES DSM IP Assets B.V. (NL) 2016-05-04 — — EP claimed
WO-2014207002-A1 METHOD FOR PRODUCING 2-(4-N,N-DIALKYLAMINO-2-HYDROXYBENZOYL) BENZOATES DSM IP ASSETS B.V. (NL) 2014-12-31 — — WO claimed
US-20050165099-A1 Method for producing 2-(4-n,n-dialkylamino-2-hydroxybenzol)benzoates BASF AKTIENGESELLSCHAFT (DE) 2005-07-28 — — US claimed
JP-2045568-A — — None — — JP disclosed
JP-63230692-A — — None — — JP disclosed
JP-11349831-A — — None — — JP disclosed
JP-56109252-A — — None — — JP disclosed
JP-9309272-A — — None — — JP disclosed
US-9682920-B2 Method for producing 2-(4-N,N-dialkylamino-2-hydroxybenzoyl) benzoates DSM IP ASSETS B.V. (NL) 2017-06-20 — — US disclosed
US-9682920-B2 Method for producing 2-(4-N,N-dialkylamino-2-hydroxybenzoyl) benzoates DSM IP ASSETS B.V. (NL) 2017-06-20 — — US disclosed
US-9682920-B2 Method for producing 2-(4-N,N-dialkylamino-2-hydroxybenzoyl) benzoates DSM IP ASSETS B.V. (NL) 2017-06-20 — — US disclosed
JP-S56109252-A PRODUCTION OF FLUORAN DERIVATIVE FUJI PHOTO FILM CO LTD 1981-08-29 — — JP disclosed
US-4187193-A Micro-capsules containing ureido fluoran chromogenic compounds CHAMPION INTERNATIONAL CORPORATION (US) 1980-02-05 — — US disclosed
US-4169183-A 9-Dialkylamino-spiro [6H-[1]benzopyrano[3,2-g]quinoline-6,1'(3'H)-isobenzofuran]-3'-one compounds and pressure-sensitive recording system therewith MOORE BUSINESS FORMS, INC. (US) 1979-09-25 — — US disclosed
US-4110343-A Bisfluoran chromogenic compounds, preparation thereof, and pressure-sensitive copy systems employing same CHAMPION INTERNATIONAL CORPORATION (US) 1978-08-29 — — US disclosed
US-4110343-A Bisfluoran chromogenic compounds, preparation thereof, and pressure-sensitive copy systems employing same CHAMPION INTERNATIONAL CORPORATION (US) 1978-08-29 — — US disclosed
US-4104437-A Pressure-sensitive copy system including ureido fluoran chromogenic compounds CHAMPION INTERNATIONAL CORPORATION (US) 1978-08-01 — — US disclosed
US-4012419-A Bisfluoran chromogenic compounds, preparation thereof, and pressure-sensitive copy systems employing same CHAMPION INTERNATIONAL CORPORATION (US) 1977-03-15 — — US disclosed
US-4012419-A Bisfluoran chromogenic compounds, preparation thereof, and pressure-sensitive copy systems employing same CHAMPION INTERNATIONAL CORPORATION (US) 1977-03-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050165099-A1 Method for producing 2-(4-n,n-dialkylamino-2-hydroxybenzol)benzoates ADH1C, ADH5, ADH1A KMT2A 1310/4885MEN1 2986/4885SMN1; SMN2 4645/4885
US-20160152554-A1 METHOD FOR PRODUCING 2-(4-N,N-DIALKYLAMINO-2-HYDROXYBENZOYL) BENZOATES HAAO, HAO2, HPD KMT2A 1038/4885MEN1 3880/4885SMN1; SMN2 3951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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