Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.33 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536646 | 0.82 | IDO1 (0.41) | TSHRTP53CYP3A4ALDH1A1TDP1 | |
| SCHEMBL10537822 | 0.82 | TSHR (0.41) | TSHRTP53CYP3A4MEN1KMT2A | |
| SCHEMBL9629161 | 0.81 | CYP3A4 (0.40) | TSHRCYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9808986 | 0.79 | CYP3A4 (0.42) | TSHRTP53CYP3A4MAOAALDH1A1 | |
| SCHEMBL11659032 | 0.79 | CYP3A4 (0.42) | TSHRTP53CYP3A4MEN1KMT2A | |
| SCHEMBL10923598 | 0.78 | MEN1 (0.50) | TSHRTP53CYP3A4MEN1KMT2A | |
| SCHEMBL9228682 | 0.74 | POLB (0.33) | ALDH1A1MAPT | |
| SCHEMBL29359062 | 0.73 | TP53 (0.36) | TP53MEN1KMT2ALMNA | |
| SCHEMBL310582 | 0.71 | MEN1 (0.50) | TSHRTP53CYP3A4MEN1KMT2A | |
| SCHEMBL9808930 | 0.70 | HSD17B10 (0.51) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215312-B1 | METHOD FOR PRODUCING OF POLYARYLENE SULFIDES | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |
| US-4810773-A | HIGH MOLECULAR WEIGHT ENGINEERING THERMOPLASTICS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0296250-A1 | POLYARYLENE SULFIDE AND PROCESS FOR ITS PRODUCTION | IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0215312-A1 | Method for producing of polyarylene sulfides | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |