Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CCNH | P51946 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231502 | 0.83 | ADRB2 (0.33) | ALDH1A1HTT | |
| SCHEMBL9231390 | 0.78 | TRPA1 (0.34) | POLBALDH1A1MAPTHTT | |
| SCHEMBL9629034 | 0.74 | TSHR (0.41) | ALDH1A1MAPT | |
| SCHEMBL10536646 | 0.74 | IDO1 (0.41) | ALDH1A1 | |
| SCHEMBL10537822 | 0.74 | TSHR (0.41) | ALDH1A1MAPT | |
| SCHEMBL9232827 | 0.73 | NPC1 (0.36) | — | |
| SCHEMBL7227231 | 0.71 | POLB (0.53) | POLBALDH1A1MAPTHTT | |
| SCHEMBL9232619 | 0.71 | ALDH1A1 (0.41) | POLBALDH1A1MAPT | |
| SCHEMBL9228146 | 0.71 | ATM (0.35) | CDK2ALDH1A1MAPT | |
| SCHEMBL9230307 | 0.70 | ALDH1A1 (0.37) | POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666253-A1 | N-t-BUTYLANILINE ANALOG AND LIPID LEVEL DEPRESSANT CONTAINING THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-08-09 | — | — | EP | disclosed |