Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629034 | 0.82 | TSHR (0.41) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL10536646 | 0.82 | IDO1 (0.41) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL10539500 | 0.81 | HSD17B10 (0.40) | TSHRHSD17B10ALDH1A1CYP3A4MEN1 | |
| SCHEMBL7935399 | 0.78 | MAPK1 (0.46) | HSD17B10ALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL9228682 | 0.74 | POLB (0.33) | ALDH1A1MAPT | |
| SCHEMBL29359062 | 0.73 | TP53 (0.36) | TP53MEN1KMT2A | |
| SCHEMBL18338 | 0.71 | CA1 (0.50) | HSD17B10ALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL9808930 | 0.70 | HSD17B10 (0.51) | TSHRHSD17B10ALDH1A1TDP1MEN1 | |
| SCHEMBL11580901 | 0.69 | MAOB (0.43) | ALDH1A1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL11748444 | 0.69 | MAOB (0.40) | ALDH1A1CYP3A4MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810773-A | HIGH MOLECULAR WEIGHT ENGINEERING THERMOPLASTICS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0215312-A1 | Method for producing of polyarylene sulfides | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |