SCHEMBL9629035

SCHEMBL9629035

Brc1cc(Br)c(Nc2ccccc2)cc1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.48
MEN1 O00255 7/20 0.46
KMT2A Q03164 7/20 0.46
MAPT P10636 7/20 0.46
GAA P10253 6/20 0.46
TDP1 Q9NUW8 5/20 0.46
KDM4E B2RXH2 5/20 0.46
GLA P06280 2/20 0.46
RECQL P46063 1/20 0.46
ALDH1A1 P00352 7/20 0.46
AR P10275 1/20 0.46
ALOX15 P16050 3/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 2/20 0.46
ALOX12 P18054 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
PTGS2 P35354 1/20 0.46
HTR2B P41595 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16615575 0.95 HSD17B10 (0.52) HSD17B10MEN1KMT2AMAPTGAA
SCHEMBL22045336 0.84 GAA (0.50) HSD17B10MEN1KMT2AMAPTGAA
SCHEMBL27906204 0.81 GAA (0.47) HSD17B10MEN1KMT2AMAPTGAA
SCHEMBL18687129 0.78 ALK (0.51) HSD17B10MEN1KMT2AMAPTGAA
SCHEMBL28598854 0.78 ALDH1A1 (0.54) HSD17B10MEN1KMT2AMAPTGAA
SCHEMBL14428159 0.78 ALK (0.51) HSD17B10MEN1KMT2AMAPTGAA
SCHEMBL3270611 0.76 MAPT (0.56) HSD17B10MEN1KMT2AMAPTGAA
SCHEMBL31425489 0.76 MAPT (0.56) HSD17B10MEN1KMT2AMAPTGAA
SCHEMBL30683251 0.75 MAPT (0.39) HSD17B10MEN1KMT2AMAPTGAA
SCHEMBL22204652 0.75 L3MBTL1 (0.50) HSD17B10MEN1KMT2AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0215312-B1 METHOD FOR PRODUCING OF POLYARYLENE SULFIDES IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1992-03-25 EP disclosed
US-4810773-A HIGH MOLECULAR WEIGHT ENGINEERING THERMOPLASTICS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1989-03-07 US disclosed
EP-0215312-A1 Method for producing of polyarylene sulfides IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1987-03-25 EP disclosed