SCHEMBL22204652

SCHEMBL22204652

Clc1ccc(Br)c(Nc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
CXCR2 P25025 3/20 0.47
ALDH1A1 P00352 6/20 0.46
TDP1 Q9NUW8 4/20 0.46
GAA P10253 3/20 0.46
HTT P42858 3/20 0.46
ALOX15 P16050 2/20 0.46
GRIK1 P39086 3/20 0.45
FADS1 O60427 1/20 0.42
HSD17B10 Q99714 2/20 0.41
MEN1 O00255 5/20 0.41
MAPT P10636 5/20 0.41
KMT2A Q03164 5/20 0.41
KDM4E B2RXH2 3/20 0.41
GLA P06280 2/20 0.41
RECQL P46063 1/20 0.41
IDO1 P14902 1/20 0.41
LMNA P02545 3/20 0.40
NPC1 O15118 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706057 1.00 L3MBTL1 (0.50) L3MBTL1CXCR2ALDH1A1TDP1GAA
SCHEMBL21835039 0.85 L3MBTL1 (0.54) L3MBTL1CXCR2ALDH1A1TDP1GAA
SCHEMBL26894571 0.82 L3MBTL1 (0.59) L3MBTL1CXCR2ALDH1A1TDP1GAA
SCHEMBL22884563 0.81 CYP2A6 (0.50) L3MBTL1CXCR2ALDH1A1TDP1GAA
SCHEMBL22934022 0.80 ALDH1A1 (0.48) L3MBTL1CXCR2ALDH1A1TDP1GAA
SCHEMBL18687129 0.80 ALK (0.51) L3MBTL1ALDH1A1TDP1GAAHTT
SCHEMBL6669652 0.80 ALDH1A1 (0.53) L3MBTL1CXCR2ALDH1A1TDP1GAA
SCHEMBL16615575 0.79 HSD17B10 (0.52) L3MBTL1ALDH1A1TDP1GAAHTT
SCHEMBL16352569 0.78 GAA (0.51) L3MBTL1CXCR2ALDH1A1TDP1GAA
SCHEMBL24126449 0.78 SMN1; SMN2 (0.43) GAAHTTLMNANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058758-A Organic electroluminescent device and polycyclic compound for organic electroluminescent device 三星显示有限公司 2025-05-30 CN disclosed
CN-111434666-B Organic electroluminescent device and polycyclic compound for organic electroluminescent device 三星显示有限公司 2025-03-21 CN disclosed
US-20240107871-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-03-28 US disclosed
US-11825733-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
US-11825733-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
US-11825733-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
CN-111434666-A Organic electroluminescent device and polycyclic compound for organic electroluminescent device 三星显示有限公司 2020-07-21 CN disclosed
US-20200227639-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-16 US disclosed
EP-3680244-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE Samsung Display Co., Ltd. (KR) 2020-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240107871-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC25A21, LEF1, KCNC1 L3MBTL1 2272/4885CXCR2 2697/4885ALDH1A1 288/4885
US-20200227639-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC25A21, LEF1, KCNC1 L3MBTL1 2272/4885CXCR2 2697/4885ALDH1A1 288/4885
US-11825733-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SLC25A21, LEF1, KCNC1 L3MBTL1 2272/4885CXCR2 2697/4885ALDH1A1 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.