Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627648 | 0.90 | MAPT (0.59) | KMT2AMAPTMEN1THRBSMN1; SMN2 | |
| SCHEMBL9628559 | 0.89 | KMT2A (0.45) | KMT2AMAPTMEN1THRBSMN1; SMN2 | |
| SCHEMBL9628223 | 0.85 | LMNA (0.57) | KMT2AMAPTMEN1THRBSMN1; SMN2 | |
| SCHEMBL9627826 | 0.82 | LMNA (0.46) | KMT2AMAPTMEN1THRBSMN1; SMN2 | |
| SCHEMBL9627615 | 0.81 | LMNA (0.45) | KMT2AMAPTMEN1THRBSMN1; SMN2 | |
| SCHEMBL9627672 | 0.80 | LMNA (0.55) | MAPTSMN1; SMN2LMNAESR1CYP3A4 | |
| SCHEMBL10649796 | 0.80 | LMNA (0.44) | KMT2AMAPTMEN1THRBSMN1; SMN2 | |
| SCHEMBL9628216 | 0.79 | MAPT (0.55) | KMT2AMAPTMEN1THRBSMN1; SMN2 | |
| SCHEMBL26659900 | 0.78 | CYP3A4 (0.66) | KMT2AMAPTMEN1THRBSMN1; SMN2 | |
| SCHEMBL3322364 | 0.78 | CYP3A4 (0.66) | KMT2AMAPTMEN1THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318490-B1 | 14,17-G(B)-ETHANO-14-G(B)-ESTRATRIENES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | disclosed |