Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817819 | 0.84 | ALDH1A1 (1.00) | HSD17B10ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL9630779 | 0.79 | BRD4 (0.54) | HSD17B10ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL9629512 | 0.79 | BRD4 (0.71) | HSD17B10ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL9629592 | 0.76 | BRD4 (0.54) | HSD17B10ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL9628743 | 0.74 | BRD4 (0.51) | HSD17B10ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL11842020 | 0.73 | ALDH1A1 (0.53) | HSD17B10ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL3053841 | 0.71 | DDB1 (0.65) | HSD17B10ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL44650 | 0.71 | SIGMAR1 (0.44) | HSD17B10ALDH1A1TSHRSMN1; SMN2GSK3B | |
| SCHEMBL3626456 | 0.70 | CA2 (0.62) | HSD17B10ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL9602657 | 0.70 | SMN1; SMN2 (0.72) | HSD17B10ALDH1A1TSHRSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |
| US-3953469-A | TRANQUILLIZERS | E. R. SQUIBB & SONS, INC. (US) | 1976-04-27 | — | — | US | disclosed |