Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629700 | 0.74 | BRD4 (0.57) | MEN1KMT2AALDH1A1GAABRD4 | |
| SCHEMBL9630822 | 0.74 | TSHR (0.38) | MEN1KMT2AALDH1A1GAAIDO1 | |
| SCHEMBL19470001 | 0.73 | MEN1 (0.51) | MEN1KMT2AALDH1A1GAAIDO1 | |
| SCHEMBL27303967 | 0.73 | MEN1 (0.47) | MEN1KMT2AALDH1A1GAAIDO1 | |
| SCHEMBL21311779 | 0.71 | IDO1 (0.47) | MEN1KMT2AALDH1A1GAAIDO1 | |
| SCHEMBL11842020 | 0.71 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1GAASIGMAR1 | |
| SCHEMBL30468213 | 0.69 | IDO1 (0.48) | MEN1KMT2AALDH1A1GAAIDO1 | |
| SCHEMBL29051604 | 0.69 | IDO1 (0.48) | MEN1KMT2AALDH1A1GAAIDO1 | |
| SCHEMBL14159608 | 0.69 | SIGMAR1 (0.42) | SIGMAR1PRCPMAPK1 | |
| SCHEMBL30468219 | 0.68 | IDO1 (0.47) | MEN1KMT2AALDH1A1GAAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |