Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441332 | 0.87 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL3623346 | 0.81 | HSD17B10 (0.56) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL27303967 | 0.76 | MEN1 (0.47) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL19470001 | 0.76 | MEN1 (0.51) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL9628805 | 0.73 | HSD17B10 (0.72) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL9629617 | 0.71 | MEN1 (0.42) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL2362161 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL7269831 | 0.69 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL7271246 | 0.69 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL9817819 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953469-A | TRANQUILLIZERS | E. R. SQUIBB & SONS, INC. (US) | 1976-04-27 | — | — | US | disclosed |