Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 10/20 | 0.64 |
| ▸ | BRD4 | O60885 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853797 | 0.78 | CREBBP (1.00) | CREBBPBRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8853352 | 0.78 | ALDH1A1 (0.66) | CREBBPBRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9629696 | 0.75 | CREBBP (0.71) | CREBBPBRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13323 | 0.74 | ALDH1A1 (0.60) | CREBBPBRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1347231 | 0.74 | CREBBP (1.00) | CREBBPBRD4ALDH1A1EP300CRBN | |
| Hydrochloric Acid SCHEMBL30648399 | 0.73 | ALDH1A1 (0.58) | CREBBPBRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1756087 | 0.72 | HDAC1 (0.51) | CREBBPBRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9143990 | 0.72 | ALDH1A1 (0.53) | CREBBPBRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10353037 | 0.71 | BRD4 (0.66) | CREBBPBRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11069336 | 0.71 | BRD4 (0.66) | CREBBPBRD4ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |