Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 7/20 | 0.46 |
| ▸ | FNTB | P49356 | 5/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.42 |
| ▸ | SQLE | Q14534 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629748 | 1.00 | ALDH1A1 (0.47) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL9629657 | 0.81 | ALOX15 (0.53) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL9629653 | 0.81 | ALOX15 (0.53) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL15370334 | 0.79 | KMT2A (0.61) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL14077034 | 0.79 | KMT2A (0.61) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL6442176 | 0.79 | KMT2A (0.61) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL1704546 | 0.79 | KMT2A (0.61) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL6442169 | 0.79 | KMT2A (0.61) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL560299 | 0.77 | ALOX15 (0.58) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL560298 | 0.77 | ALOX15 (0.58) | ALDH1A1ALOX15KMT2AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5107011-A | Intermediates for anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-04-21 | — | — | US | claimed |