Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 7/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9629740 | 0.99 | FEN1 (0.50) | FEN1ALDH1A1KDM4EPDE4APDE4B | |
| Pirodomast SCHEMBL125348 | 0.99 | FEN1 (0.52) | FEN1ALDH1A1KDM4EPDE4APDE4B | |
| Pirodomast SCHEMBL29385413 | 0.99 | FEN1 (0.52) | FEN1ALDH1A1KDM4EPDE4APDE4B | |
| Pirodomast SCHEMBL9488218 | 0.98 | FEN1 (0.51) | FEN1ALDH1A1KDM4EPDE4APDE4B | |
| SCHEMBL9629745 | 0.87 | FEN1 (0.48) | FEN1ALDH1A1KDM4EPDE4APDE4B | |
| Water SCHEMBL10427748 | 0.87 | MAPT (0.44) | FEN1ALDH1A1KDM4EPDE4BPDE4D | |
| Water SCHEMBL9629016 | 0.86 | FEN1 (0.47) | FEN1ALDH1A1KDM4EPDE4APDE4B | |
| Pirodomast SCHEMBL607268 | 0.86 | LOXL3 (0.43) | FEN1ALDH1A1KDM4EPDE4APDE4B | |
| Water SCHEMBL10582943 | 0.84 | FEN1 (0.46) | FEN1ALDH1A1PDE4APDE4BPDE4C | |
| Water SCHEMBL10580186 | 0.81 | ALDH1A1 (0.43) | FEN1ALDH1A1KDM4EPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232328-B1 | ZWITTERIONIC BICYCLIC COMPOUNDS AND THEIR SALTS, SOLVATES, HYDRATES AND ESTERS | SCHERING CORPORATION (US) | 1992-04-15 | — | — | EP | claimed |
| EP-0338010-B1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF HYPERPROLIFERATE SKIN DISEASE | SCHERING CORPORATION (US) | 1992-02-05 | — | — | EP | claimed |